Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648528 | 0.94 | PTPN1 (0.49) | PTPN1PTPN2 | |
| SCHEMBL647691 | 0.87 | PTPN1 (0.49) | PTPN1PTPN2 | |
| SCHEMBL2937436 | 0.84 | PTPN1 (0.53) | PTPN1PTPN2 | |
| SCHEMBL2935548 | 0.82 | PTPN1 (0.53) | PTPN1PTPN2 | |
| SCHEMBL3076419 | 0.81 | PTPN1 (0.51) | PTPN1PTPN2 | |
| SCHEMBL2933409 | 0.81 | PTPN1 (0.55) | PTPN1PTPN2 | |
| SCHEMBL2937682 | 0.80 | PTPN1 (0.56) | PTPN1PTPN2 | |
| SCHEMBL2937386 | 0.80 | PTPN1 (0.58) | PTPN1PTPN2 | |
| SCHEMBL2936009 | 0.73 | PTPN1 (0.60) | PTPN1PTPN2 | |
| SCHEMBL2937823 | 0.73 | PTPN1 (0.52) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119666-B2 | 1,2,5-thiazolidine derivatives useful for treating conditions mediated by protein tyrosine phosphatases (PTPase) | NOVARTIS AG (CH) | 2012-02-21 | — | — | US | claimed |
| US-8119666-B2 | 1,2,5-thiazolidine derivatives useful for treating conditions mediated by protein tyrosine phosphatases (PTPase) | NOVARTIS AG (CH) | 2012-02-21 | — | — | US | disclosed |