SCHEMBL6459792

SCHEMBL6459792

C=CCCc1ccc(-c2ccc(C3CCC4CC(CCCC)CCC4C3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 13/20 0.38
SPHK2 Q9NRA0 7/20 0.34
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6459789 1.00 SPHK1 (0.38) SPHK1SPHK2CYP2C9
SCHEMBL6453322 0.97 SPHK1 (0.40) SPHK1SPHK2CYP2C9
SCHEMBL6453328 0.97 SPHK1 (0.40) SPHK1SPHK2CYP2C9
SCHEMBL6455789 0.96 SPHK1 (0.42) SPHK1SPHK2CYP2C9
SCHEMBL6459243 0.96 SPHK1 (0.42) SPHK1SPHK2CYP2C9
SCHEMBL6459247 0.96 SPHK1 (0.42) SPHK1SPHK2CYP2C9
SCHEMBL6455793 0.96 SPHK1 (0.42) SPHK1SPHK2CYP2C9
SCHEMBL6457179 0.90 SPHK1 (0.36) SPHK1SPHK2CYP2C9
SCHEMBL6457175 0.90 SPHK1 (0.36) SPHK1SPHK2CYP2C9
SCHEMBL6460278 0.89 SPHK1 (0.33) SPHK1SPHK2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed
EP-1108700-A1 DECAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-20 EP disclosed