SCHEMBL6460320

SCHEMBL6460320

CCCCCC1CCC2CC(c3ccc(-c4cc(F)c(OC(F)(F)F)c(F)c4)cc3)CCC2C1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
CNR1 P21554 2/20 0.31
CNR2 P34972 2/20 0.31
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6460315 1.00 GAA (0.31) GAAMAPTCNR1CNR2CYP2C9
SCHEMBL6460303 0.99 GAA (0.33) GAAMAPTCNR1CNR2
SCHEMBL6455130 0.99 GAA (0.33) GAAMAPTCNR1CNR2
SCHEMBL6455127 0.99 GAA (0.33) GAAMAPTCNR1CNR2
SCHEMBL6460299 0.99 GAA (0.33) GAAMAPTCNR1CNR2
SCHEMBL6459558 0.97 CNR1 (0.32) CNR1CNR2CYP2C9
SCHEMBL6459553 0.97 CNR1 (0.32) CNR1CNR2CYP2C9
SCHEMBL6464682 0.93 CYP2C9 (0.36) MAPTCYP2C9
SCHEMBL6464684 0.93 CYP2C9 (0.36) MAPTCYP2C9
SCHEMBL6464915 0.91 GAA (0.32) GAAMAPTCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed
EP-1108700-A1 DECAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-20 EP disclosed