Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.70 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.70 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14006817 | 0.99 | DPP4 (0.71) | DPP4DPP7DPP8CYP3A4 | |
| SCHEMBL8483179 | 0.87 | DPP4 (0.67) | DPP4DPP7DPP8CYP3A4DPP9 | |
| SCHEMBL8474386 | 0.86 | DPP4 (0.65) | DPP4DPP7DPP8CYP3A4DPP9 | |
| SCHEMBL8491036 | 0.84 | DPP4 (0.60) | DPP4DPP7DPP8CYP3A4 | |
| SCHEMBL8481902 | 0.84 | DPP4 (0.60) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL8473641 | 0.84 | DPP4 (0.64) | DPP4DPP7DPP8CYP3A4DPP9 | |
| SCHEMBL8474394 | 0.83 | DPP4 (0.61) | DPP4DPP7DPP8CYP3A4DPP9 | |
| SCHEMBL8491016 | 0.83 | DPP4 (0.61) | DPP4DPP7DPP8CYP3A4DPP9 | |
| SCHEMBL4956199 | 0.82 | DPP4 (0.58) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL8290155 | 0.82 | DPP4 (0.58) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1541143-A1 | DPP-IV INHIBITORS | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2005-06-15 | — | — | EP | disclosed |