Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10279476 | 0.89 | ATM (0.51) | ATMALDH1A1KDM4ENAMPTRAB9A | |
| SCHEMBL647508 | 0.85 | ATM (0.47) | ATMALDH1A1KDM4ENAMPTRAB9A | |
| SCHEMBL647509 | 0.85 | ATM (0.47) | ATMALDH1A1KDM4ENAMPTRAB9A | |
| SCHEMBL16133857 | 0.83 | ATM (0.53) | ATMNAMPTRAB9AL3MBTL1CYP1A2 | |
| SCHEMBL645503 | 0.83 | ATM (0.76) | ATMALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL10238235 | 0.83 | ATM (0.46) | ATMALDH1A1KDM4ENAMPTRAB9A | |
| SCHEMBL647342 | 0.82 | ATM (0.52) | ATMNAMPTRAB9AL3MBTL1CYP1A2 | |
| SCHEMBL10238472 | 0.81 | ATM (0.49) | ATMALDH1A1KDM4ENAMPTRAB9A | |
| SCHEMBL10238297 | 0.80 | ATM (0.50) | ATMALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL8234005 | 0.78 | NAMPT (0.39) | ATMALDH1A1NAMPTRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628962-B1 | Iodopyrazolyl carboxanilides | BAYER IP GMBH (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-1628962-B1 | Iodopyrazolyl carboxanilides | BAYER IP GMBH (DE) | 2014-10-01 | — | — | EP | disclosed |
| US-8119682-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119682-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119682-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
| US-7906656-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-7906656-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20100152266-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20100152266-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-7687531-B2 | N-(3',4'dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-iodo-1-methyl-1H-pyrazole4-carboxamide; fungicides; molds/fungi/; plants/organisms/; controlling microorganisms; microbiocides; dermatophytes; Candida; Epidermophyton; Aspergillus; Trichophyton | BAYER CROPSCIENCE AG (DE) | 2010-03-30 | — | — | US | disclosed |
| US-7687531-B2 | N-(3',4'dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-iodo-1-methyl-1H-pyrazole4-carboxamide; fungicides; molds/fungi/; plants/organisms/; controlling microorganisms; microbiocides; dermatophytes; Candida; Epidermophyton; Aspergillus; Trichophyton | BAYER CROPSCIENCE AG (DE) | 2010-03-30 | — | — | US | disclosed |
| US-7687531-B2 | N-(3',4'dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-iodo-1-methyl-1H-pyrazole4-carboxamide; fungicides; molds/fungi/; plants/organisms/; controlling microorganisms; microbiocides; dermatophytes; Candida; Epidermophyton; Aspergillus; Trichophyton | BAYER CROPSCIENCE AG (DE) | 2010-03-30 | — | — | US | disclosed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
| EP-1628962-A1 | IODOPYRAZOLYL CARBOXANILIDES | Bayer CropScience AG (DE) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004103975-A1 | IODOPYRAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | IDH2, ABL1, IDH1 | ATM 1738/4885ALDH1A1 804/4885KDM4E 2590/4885 |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | Q6ZSR9, C1S, MRPL21 | ATM 2268/4885ALDH1A1 1194/4885KDM4E 2214/4885 |
| US-20100152266-A1 | Iodopyrazolyl Carboxanilides | IDH2, ABL1, IDH1 | ATM 1738/4885ALDH1A1 804/4885KDM4E 2590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.