Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451705 | 1.00 | GRM2 (0.33) | GRM2SLC6A4LRRK2SLC6A2SLC6A3 | |
| SCHEMBL6451709 | 1.00 | GRM2 (0.33) | GRM2SLC6A4LRRK2SLC6A2SLC6A3 | |
| SCHEMBL6460921 | 1.00 | GRM2 (0.33) | GRM2SLC6A4LRRK2SLC6A2SLC6A3 | |
| SCHEMBL6452378 | 0.99 | SLC6A4 (0.33) | GRM2SLC6A4LRRK2SLC6A2SLC6A3 | |
| SCHEMBL6452371 | 0.99 | SLC6A4 (0.33) | GRM2SLC6A4LRRK2SLC6A2SLC6A3 | |
| SCHEMBL6455943 | 0.96 | SLC6A4 (0.33) | SLC6A4LRRK2SLC6A2SLC6A3BCHE | |
| SCHEMBL6455945 | 0.96 | SLC6A4 (0.33) | SLC6A4LRRK2SLC6A2SLC6A3BCHE | |
| SCHEMBL6457373 | 0.92 | SLC6A4 (0.34) | SLC6A4LRRK2SLC6A2SLC6A3DRD3 | |
| SCHEMBL6457377 | 0.92 | SLC6A4 (0.34) | SLC6A4LRRK2SLC6A2SLC6A3DRD3 | |
| SCHEMBL6456885 | 0.88 | SLC6A4 (0.34) | SLC6A4LRRK2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |