Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460930 | 1.00 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3TP53POLB | |
| SCHEMBL6460715 | 0.97 | SLC6A4 (0.36) | SLC6A4SLC6A2SLC6A3TP53POLB | |
| SCHEMBL6460710 | 0.97 | SLC6A4 (0.36) | SLC6A4SLC6A2SLC6A3TP53POLB | |
| SCHEMBL6458690 | 0.96 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3TP53POLB | |
| SCHEMBL6458036 | 0.96 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3TP53POLB | |
| SCHEMBL6458030 | 0.96 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3TP53POLB | |
| SCHEMBL6458687 | 0.96 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3TP53POLB | |
| SCHEMBL6456652 | 0.93 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3MAPTDRD2 | |
| SCHEMBL6456648 | 0.93 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3MAPTDRD2 | |
| SCHEMBL6458258 | 0.89 | TP53 (0.34) | TP53OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |