SCHEMBL6461860

SCHEMBL6461860

CC1=C2c3cc(C)oc3C1[Si]2(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546928 0.73 CHRM2 (0.30)
SCHEMBL6456571 0.69
SCHEMBL6455046 0.63
SCHEMBL13600314 0.51 TDP1 (0.45)
SCHEMBL11928939 0.49 NQO1 (0.48)
SCHEMBL5039621 0.49 NQO1 (0.47)
SCHEMBL13672157 0.46 NQO1 (0.38)
SCHEMBL182910 0.46
SCHEMBL9586 0.46
SCHEMBL15918971 0.46 CA1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6949614-B1 Catalyst system BASELL POLYOLEFINE GMBH (DE) 2005-09-27 US disclosed
EP-1175262-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2004-02-18 EP disclosed
EP-1290002-B1 CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2004-01-21 EP disclosed
EP-0812891-B1 Coatings based on perfluoropolyethers SOLVAY SOLEXIS SPA (IT) 2003-10-01 EP disclosed
EP-1344807-A2 Coatings based on perfluoropolyethers Solvay Solexis S.p.A. (IT) 2003-09-17 EP disclosed
US-6071564-A COATING AND PROTECTING SUBSTRATES WITH PERFLUOROPOLYETHERAL PREPOLYMERS AND POLYISOCYANATES FOR POLYURETHANES PROTECTIVE COATINGS AUSIMONT S.P.A. (IT) 2000-06-06 US disclosed
EP-0812891-A2 Coatings based on perfluoropolyethers Ausimont S.p.A. (IT) 1997-12-17 EP disclosed