SCHEMBL646321

SCHEMBL646321

NOP(N)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37030 0.74
SCHEMBL2004813 0.70
SCHEMBL17554287 0.70
SCHEMBL16585823 0.70
SCHEMBL11497448 0.70
SCHEMBL1500470 0.70
SCHEMBL16581338 0.67
SCHEMBL442336 0.67
SCHEMBL14157317 0.67
SCHEMBL153732 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1278803-B1 SULFONATED ¬8,9 BENZOPHENOXAZINE DYES AND THE USE OF THEIR LABELLED CONJUGATES APPLIED BIOSYSTEMS (US) 2008-12-17 EP claimed
US-20030158407-A1 Sulfonated [8,9] benzophenoxazine dyes and the use of their labelled conjugates APPLERA CORPORATION 2003-08-21 US claimed
EP-1278803-A2 SULFONATED 8,9]BENZOPHENOXAZINE DYES AND THE USE OF THEIR LABELLED CONJUGATES Applera Corporation (US) 2003-01-29 EP claimed
US-6465644-B1 CAN BE CONJUGATED TO A VARIETY OF SUBSTRATES, SUCH AS POLYNUCLEOTIDES, NUCLEOSIDES, NUCLEOTIDES, PEPTIDES, PROTEINS, ANTIBODIES, CARBOHYDRATES, LIGANDS, PARTICLES AND SURFACES. APPLERA CORPORATION 2002-10-15 US claimed
WO-2001083621-A2 SULFONATED [8,9]BENZOPHENOXAZINE DYES AND THE USE OF THEIR LABELLED CONJUGATES APPLERA CORPORATION (US) 2001-11-08 WO claimed
US-20260078372-A1 NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF LPA IN A CELL SILENCE THERAPEUTICS GMBH (DE) 2026-03-19 US disclosed
EP-4694931-A1 EXTRAHEPATIC DELIVERY OF DOUBLE-STRANDED RNA AGENTS Alnylam Pharmaceuticals, Inc. (US) 2026-02-18 EP disclosed
US-12421516-B2 Antisense oligomers targeting PCSK9 ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) 2025-09-23 US disclosed
US-12357698-B1 FUS proteolysis-targeting chimera, preparation method and applications thereof SHANDONG NORMAL UNIVERSITY (CN) 2025-07-15 US disclosed
CN-118750470-B Preparation method, product and application of cyclophosphamide sodium alginate nanoparticle 广东医科大学附属医院 2025-06-10 CN disclosed
CN-119842706-A Nucleic acid for inhibiting expression of LPA in cells 赛伦斯治疗有限责任公司 2025-04-18 CN disclosed
EP-4523681-A1 AMORPHOUS SOLID SUCCINYLATED 3-(FATTY ACID AMIDO)-2-HYDROXY-1-(PROTECTED HYDROXY)-PROPANE SALTS AND METHODS OF MAKING THE SAME Geron Corporation (US) 2025-03-19 EP disclosed
EP-0562014-A4 1994-02-23 EP disclosed
EP-0380559-B1 OLIGONUCLEOTIDE FUNCTIONALIZING REAGENTS AND METHODS CETUS ONCOLOGY CORP (US) 1993-12-22 EP disclosed
EP-0562014-A1 METHODS FOR LABELLING OLIGONUCLEOTIDES ABBOTT LABORATORIES (US) 1993-09-29 EP disclosed
EP-0315499-B1 NUCLEOSIDE DERIVATIVES, PARTICULARLY OF 2'-DEOXYCYTIDINE, AND THEIR USE IN THE SYNTHESIS OF OLIGONUCLEOTIDES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1993-04-07 EP disclosed
WO-1992010505-A1 METHODS FOR LABELLING OLIGONUCLEOTIDES ABBOTT LABORATORIES (US) 1992-06-25 WO disclosed
EP-0380559-A1 OLIGONUCLEOTIDE FUNCTIONALIZING REAGENTS AND METHODS. CETUS CORP (US) 1990-08-08 EP disclosed
US-4914210-A Oligonucleotide functionalizing reagents CETUS CORPORATION (US) 1990-04-03 US disclosed
WO-1989002931-A1 OLIGONUCLEOTIDE FUNCTIONALIZING REAGENTS AND METHODS CETUS CORPORATION (US) 1989-04-06 WO disclosed