Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463237 | 1.00 | GRM2 (0.38) | GRM2FASNMMP12FFAR4KDM1A | |
| SCHEMBL6452813 | 0.94 | GRM2 (0.37) | GRM2FASNMMP12FFAR4KDM1A | |
| SCHEMBL6452806 | 0.94 | GRM2 (0.37) | GRM2FASNMMP12FFAR4KDM1A | |
| SCHEMBL6459857 | 0.93 | GRM2 (0.36) | GRM2FASNMMP12FFAR4KDM1A | |
| SCHEMBL6459852 | 0.93 | GRM2 (0.36) | GRM2FASNMMP12FFAR4KDM1A | |
| SCHEMBL6457427 | 0.92 | GRM2 (0.36) | GRM2FASNMMP12FFAR4KDM1A | |
| SCHEMBL6453639 | 0.92 | GRM2 (0.36) | GRM2FASNMMP12FFAR4KDM1A | |
| SCHEMBL6457432 | 0.92 | GRM2 (0.36) | GRM2FASNMMP12FFAR4KDM1A | |
| SCHEMBL6453644 | 0.92 | GRM2 (0.36) | GRM2FASNMMP12FFAR4KDM1A | |
| SCHEMBL6455015 | 0.92 | GRM2 (0.39) | GRM2FASNMMP12FFAR4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |