SCHEMBL6463318

SCHEMBL6463318

C=CC(=C)C.C=CC(=O)OCCCC

nearest known ligand 0.85

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.85
HPGD P15428 1/20 0.85
ALDH1A1 P00352 4/20 0.61
CYP3A4 P08684 1/20 0.61
ATM Q13315 1/20 0.59
HCAR2 Q8TDS4 3/20 0.52
TP53 P04637 2/20 0.50
HIF1A Q16665 2/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 3/20 0.46
MAPT P10636 1/20 0.45
RAB9A P51151 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
APP P05067 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27914900 0.98 TSHR (0.81) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL3195579 0.94 TSHR (0.88) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL11810623 0.94 TSHR (0.88) TSHRHPGDALDH1A1CYP3A4ATM
Acetone SCHEMBL9319476 0.92 TSHR (0.92) TSHRHPGDALDH1A1CYP3A4ATM
Zinc Ion SCHEMBL28175135 0.92 TSHR (0.92) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1330627 0.92
SCHEMBL15037 0.92
SCHEMBL5681395 0.92 TSHR (1.00) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1331857 0.92
SCHEMBL11582291 0.92 TSHR (1.00) TSHRHPGDALDH1A1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3075748-B1 METHOD FOR PRODUCING POLYMERS WITH RADICAL POLYMERIZATION INITIATOR ZEON CORP (JP) 2020-11-18 EP disclosed
US-10689336-B2 Radical polymerization initiator and method for producing polymers ZEON CORPORATION (JP) 2020-06-23 US disclosed
CN-107075002-B The manufacturing method of conjugated diolefin polymer 日本瑞翁株式会社 2019-11-19 CN disclosed
US-20190292146-A1 RADICAL POLYMERIZATION INITIATOR AND METHOD FOR PRODUCING POLYMERS KYOTO UNIVERSITY (JP) 2019-09-26 US disclosed
CN-105745230-B Radical polymerization initiator and method for producing polymer 日本瑞翁株式会社 2019-08-13 CN disclosed
US-10351650-B2 Method for producing conjugated diene polymer ZEON CORPORATION (JP) 2019-07-16 US disclosed
US-20190144587-A1 METHOD FOR PRODUCING CONJUGATED DIENE POLYMER ZEON CORPORATION (JP) 2019-05-16 US disclosed
US-20190092890-A1 METHOD FOR PRODUCING COPOLYMER, AND METHOD FOR PRODUCING LATEX ZEON CORPORATION (JP) 2019-03-28 US disclosed
EP-3438136-A1 METHOD FOR PRODUCING COPOLYMER, AND METHOD FOR PRODUCING LATEX Zeon Corporation (JP) 2019-02-06 EP disclosed
CN-108779193-A The manufacturing method of copolymer and the manufacturing method of latex 日本瑞翁株式会社 2018-11-09 CN disclosed
EP-3214099-A1 METHOD FOR PRODUCING CONJUGATED DIENE POLYMER Zeon Corporation (JP) 2017-09-06 EP disclosed
CN-107075002-A The manufacture method of conjugated diolefin polymer 日本瑞翁株式会社 2017-08-18 CN disclosed
US-20160297755-A1 RADICAL POLYMERIZATION INITIATOR AND METHOD FOR PRODUCING POLYMERS ZEON CORPORATION (JP) 2016-10-13 US disclosed
EP-3075748-A1 RADICAL POLYMERIZATION INITIATOR AND METHOD FOR PRODUCING POLYMERS Zeon Corporation (JP) 2016-10-05 EP disclosed
CN-105745230-A Radical polymerization initiator and method for producing polymer 日本瑞翁株式会社 2016-07-06 CN disclosed
EP-1085029-B1 Process for polymerizing a methacrylic ester or an acrylic ester KURARAY CO (JP) 2005-12-14 EP disclosed
US-6767976-B2 POLYMERIZING METHACRYLIC ESTER OR ACRYLIC ESTER ANIONICALLY, USING A POLYMERIZATION INITIATOR COMPRISING ADDITION REACTION PRODUCT OF CONJUGATED DIENE COMPOUND AND ORGANIC ALKALI METAL COMPOUND AND TERTIARY ORGANOALUMINUM COMPOUND KURARAY CO., LTD. (JP) 2004-07-27 US disclosed
US-20030204033-A1 Process for polymerizing a methacrylic ester or an acrylic ester KURARAY CO., LTD. (JP) 2003-10-30 US disclosed
US-6630554-B1 Methacrylic ester or an acrylic ester is anionically polymerized, using a polymerization initiator compound omprising an addition reaction product of a conjugated diene compound and an organic alkali metal compound, in the presence KURARAY CO., LTD. (JP) 2003-10-07 US disclosed
EP-1085029-A1 Process for polymerizing a methacrylic ester or an acrylic ester KURARAY CO., LTD. (JP) 2001-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10689336-B2 Radical polymerization initiator and method for producing polymers PRMT1, ROS1, TERB1 TSHR 3550/4885HPGD 1412/4885ALDH1A1 854/4885
US-20160297755-A1 RADICAL POLYMERIZATION INITIATOR AND METHOD FOR PRODUCING POLYMERS PRMT1, ROS1, TERB1 TSHR 3550/4885HPGD 1412/4885ALDH1A1 854/4885
US-20190292146-A1 RADICAL POLYMERIZATION INITIATOR AND METHOD FOR PRODUCING POLYMERS PRMT1, ROS1, TERB1 TSHR 3550/4885HPGD 1412/4885ALDH1A1 854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.