Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | BID | P55957 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.46 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465819 | 0.98 | TSHR (0.54) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6466153 | 0.98 | TSHR (0.54) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6468288 | 0.98 | TSHR (0.54) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6464030 | 0.98 | TSHR (0.54) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6463491 | 0.95 | TSHR (0.51) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL30656414 | 0.90 | TSHR (0.53) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL29024357 | 0.89 | TSHR (0.49) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL29024331 | 0.89 | TSHR (0.49) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL28074918 | 0.89 | TSHR (0.51) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL671316 | 0.88 | TSHR (0.51) | TSHRTP53CYP3A4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951904-B1 | Process for increasing the melt strength of polypropylene | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2005-10-04 | — | — | US | claimed |
| EP-1080148-A4 | PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE | POLYMERS AUSTRALIA PTY LTD (AU) | 2003-02-05 | — | — | EP | claimed |
| EP-1080148-A1 | PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE | Polymers Australia PTY Limited (AU) | 2001-03-07 | — | — | EP | claimed |
| WO-1999036466-A1 | PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE | POLYMERS AUSTRALIA PTY LIMITED (AU) | 1999-07-22 | — | — | WO | claimed |
| US-6951904-B1 | Process for increasing the melt strength of polypropylene | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2005-10-04 | — | — | US | disclosed |
| EP-1080148-A4 | PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE | POLYMERS AUSTRALIA PTY LTD (AU) | 2003-02-05 | — | — | EP | disclosed |
| EP-1080148-A1 | PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE | Polymers Australia PTY Limited (AU) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999036466-A1 | PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE | POLYMERS AUSTRALIA PTY LIMITED (AU) | 1999-07-22 | — | — | WO | disclosed |