Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DBH | P09172 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463711 | 1.00 | DBH (0.34) | DBHTLR4HTR2AHTR2CHTR2B | |
| SCHEMBL6451204 | 0.88 | TLR4 (0.32) | TLR4 | |
| SCHEMBL6451206 | 0.88 | TLR4 (0.32) | TLR4 | |
| SCHEMBL6453736 | 0.86 | TLR4 (0.34) | TLR4 | |
| SCHEMBL6453738 | 0.86 | TLR4 (0.34) | TLR4 | |
| SCHEMBL7745981 | 0.86 | TLR4 (0.34) | TLR4 | |
| SCHEMBL6458368 | 0.86 | TLR4 (0.30) | TLR4 | |
| SCHEMBL6458363 | 0.86 | TLR4 (0.30) | TLR4 | |
| SCHEMBL6455173 | 0.83 | TLR4 (0.33) | TLR4 | |
| SCHEMBL12032046 | 0.83 | TLR4 (0.38) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |