O-Xylene

O-Xylene

SCHEMBL6463786

Cc1ccccc1C.NC(N)=O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.62
ACHE P22303 1/20 0.62
POLB P06746 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
MYC P01106 1/20 0.46
ALDH1A1 P00352 4/20 0.46
HPGD P15428 2/20 0.46
TDP1 Q9NUW8 3/20 0.46
MAPT P10636 3/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 2/20 0.46
PARP1 P09874 1/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL28151380 0.97 TSHR (0.59) TSHRACHEPOLBNPC1RAB9A
O-Xylene SCHEMBL28228345 0.94 TSHR (0.56) TSHRACHEPOLBNPC1RAB9A
O-Xylene SCHEMBL27848444 0.91 TSHR (0.59) TSHRACHEPOLBNPC1RAB9A
O-Xylene SCHEMBL8469340 0.91 TSHR (0.59) TSHRACHEPOLBNPC1RAB9A
O-Xylene SCHEMBL32679707 0.91 TSHR (0.59) TSHRACHEPOLBNPC1RAB9A
O-Xylene SCHEMBL28509799 0.84 TSHR (0.67) TSHRACHEPOLBNPC1RAB9A
O-Xylene SCHEMBL28230316 0.84 TSHR (0.67) TSHRACHEPOLBNPC1RAB9A
O-Xylene SCHEMBL510350 0.84 TSHR (0.67) TSHRACHEPOLBNPC1RAB9A
O-Xylene SCHEMBL7498508 0.84 TSHR (0.67) TSHRACHEPOLBNPC1RAB9A
O-Xylene SCHEMBL28577267 0.84 POLB (0.52) TSHRACHEPOLBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553920-A A kind of heat resistant and wear resistant damage scratching rack macromolecule resin bridge crossing plate 宝山钢铁股份有限公司 2019-04-02 CN disclosed
CN-104198448-B Probe for detecting aluminum ion, preparation method and kit including the probe 盐城师范学院 2017-05-24 CN disclosed
CN-104402837-A Preparation method of weedicide hexazinone JIANGSU LANFENG BIOCHEMICAL CO LTD 2015-03-11 CN disclosed
EP-1263701-B1 PROCESS FOR THE PREPARATION OF XYLENE DU PONT (US) 2005-05-18 EP disclosed
US-6600081-B2 Cyclization of trimethylpentane E.I. DU PONT DE NEMOURS AND COMPANY 2003-07-29 US disclosed