Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504715 | 0.89 | PPARG (0.60) | PPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6491323 | 0.88 | PPARG (0.59) | PPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6490809 | 0.88 | PPARG (0.59) | PPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6491902 | 0.87 | PPARG (0.54) | PPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6299715 | 0.86 | PPARG (0.73) | PPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6491134 | 0.85 | PPARG (0.56) | PPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6498488 | 0.85 | PPARG (0.58) | PPARG | |
| SCHEMBL6489866 | 0.85 | PPARG (0.61) | PPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6299033 | 0.85 | PPARG (0.61) | PPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6306107 | 0.85 | PPARG (0.61) | PPARGALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082414-A2 | CONCOMITANT DRUGS OF A SULFONAMIDE AND ANOTHER THERAPEUTIC AGENT | ASTELLAS PHARMA INC. (JP) | 2005-09-09 | — | — | WO | disclosed |