SCHEMBL6464503

SCHEMBL6464503

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(F)C(F)F)n1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.54
CDK1 P06493 1/20 0.42
MAPT P10636 3/20 0.40
TP53 P04637 1/20 0.40
GLA P06280 1/20 0.40
CYP1A2 P05177 1/20 0.40
KMT2A Q03164 2/20 0.39
NLRP3 Q96P20 1/20 0.36
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9267498 0.88 GAA (0.53) GAACDK1MAPTTP53GLA
SCHEMBL7453942 0.86 GAA (0.53) GAACDK1MAPTTP53GLA
SCHEMBL7457583 0.85 GAA (0.50) GAACDK1MAPTTP53GLA
SCHEMBL7452100 0.84 GAA (0.50) GAACDK1MAPTTP53GLA
SCHEMBL7455377 0.84 GAA (0.50) GAACDK1MAPTTP53GLA
SCHEMBL29176414 0.84 GAA (0.58) GAACDK1MAPTTP53GLA
SCHEMBL7455828 0.83 GAA (0.49) GAACDK1MAPTTP53GLA
SCHEMBL7455217 0.83 GAA (0.47) GAACDK1MAPTTP53GLA
SCHEMBL7452294 0.83 GAA (0.47) GAACDK1MAPTTP53GLA
SCHEMBL9522827 0.83 GAA (0.58) GAACDK1MAPTTP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115701900-A Liquid sulfonylurea herbicide compositions 巴特尔英国有限公司 2023-02-14 CN disclosed
US-20050112571-A1 Dna molecules conferring tolerance to herbicidal compounds SYNGENTA PARTICIPATIONS AG (CH) 2005-05-26 US disclosed
EP-1414982-A2 DNA MOLECULES ENCODING HERBICIDE TOLERANT ACETOLACTATE SYNTHASE Syngenta Participations AG (CH) 2004-05-06 EP disclosed
WO-2003012115-A2 DNA MOLECULES ENCODING HERBICIDE TOLERANT ACETOLACTATE SYNTHASE SYNGENTA PARTICIPATIONS AG (CH) 2003-02-13 WO disclosed
US-6159900-A Synergistic herbicidal agents HOECHST AKTIENGESELLSCHAFT (DE) 2000-12-12 US disclosed
US-5635448-A 3-SUBSTITUTED PHENYLPYRAZOLE DERIVATIVES ASAMURA PATENT OFFICE (JP) 1997-06-03 US disclosed
EP-0619946-B1 Herbicidal composition for upland farming and weeding method NIHON NOHYAKU CO LTD (JP) 1996-06-05 EP disclosed
EP-0619946-A1 Herbicidal composition for upland farming and weeding method NIHON NOHYAKU CO., LTD. (JP) 1994-10-19 EP disclosed