SCHEMBL6464651

SCHEMBL6464651

OC[C@H]1OC(O)[C@H](OOc2cccc3ncn(Cc4ccc(-n5cccn5)cc4)c23)[C@@H](O)[C@@H]1O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 4/20 0.40
▸ SLC5A1 P13866 1/20 0.40
▸ ATM Q13315 1/20 0.35
▸ CHRM1 P11229 5/20 0.33
▸ HCRTR1 O43613 1/20 0.33
▸ HCRTR2 O43614 1/20 0.33
▸ PRKAG1 P54619 1/20 0.33
▸ PRKAA2 P54646 1/20 0.33
▸ PRKAB1 Q9Y478 1/20 0.33
▸ ADORA3 P0DMS8 2/20 0.33
▸ ADORA1 P30542 2/20 0.33
▸ CSF1R P07333 1/20 0.32
▸ DRD2 P14416 1/20 0.31
▸ DRD4 P21917 1/20 0.31
▸ DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3409214 1.00 SLC5A2 (0.40) SLC5A2SLC5A1ATMCHRM1HCRTR1
SCHEMBL3406498 0.89 SLC5A2 (0.41) SLC5A2SLC5A1ADORA3
SCHEMBL3408877 0.89 SLC5A2 (0.41) SLC5A2SLC5A1ADORA3
SCHEMBL6465802 0.88 SLC5A2 (0.39) SLC5A2SLC5A1CSF1R
SCHEMBL3411019 0.88 SLC5A2 (0.39) SLC5A2SLC5A1CSF1R
SCHEMBL3410072 0.86 SLC5A2 (0.43) SLC5A2SLC5A1
SCHEMBL3407888 0.86 SLC5A2 (0.43) SLC5A2SLC5A1
SCHEMBL6468147 0.85 SLC5A2 (0.42) SLC5A2SLC5A1
SCHEMBL3407259 0.85 SLC5A2 (0.42) SLC5A2SLC5A1
SCHEMBL6464664 0.84 SLC5A2 (0.41) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050032712-A1 Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides JANSSEN PHARMACEUTICA N.V. (BE) 2005-02-10 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050032712-A1 Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides GANAB, GCG, GANC SLC5A2 18/4885SLC5A1 19/4885ATM 515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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