SCHEMBL6466331

SCHEMBL6466331

O=S(=O)(O)c1ccc2scnc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 6/20 0.44
OGA O60502 3/20 0.43
RIPK2 O43353 2/20 0.43
KDR P35968 1/20 0.43
ALDH1A1 P00352 2/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
SPPL2A Q8TCT8 1/20 0.41
HSD11B1 P28845 1/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
HKDC1 Q2TB90 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
RIPK1 Q13546 1/20 0.41
RIPK3 Q9Y572 1/20 0.41
GLRA3 O75311 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27810068 0.98 CHRM5 (0.43) CHRM5OGARIPK2KDRALDH1A1
SCHEMBL1144922 0.86 NPC1 (0.53) CHRM5ALDH1A1HSD17B10KDM4ENPC1
Hydrochloric Acid SCHEMBL27712066 0.84 NPC1 (0.51) CHRM5ALDH1A1HSD17B10KDM4ENPC1
Zinc Ion SCHEMBL7599075 0.82 RIPK2 (0.43) CHRM5OGARIPK2KDRALDH1A1
SCHEMBL11516564 0.82 RIPK2 (0.59) CHRM5OGARIPK2KDRALDH1A1
SCHEMBL4710033 0.82 RXFP1 (0.47) CHRM5OGARIPK2KDRALDH1A1
SCHEMBL3153231 0.82 RIPK2 (0.43) CHRM5OGARIPK2KDRALDH1A1
SCHEMBL8371819 0.78 IKBKB (0.48) OGARIPK2KDRALDH1A1HSD17B10
Benzo[D]Thiazole SCHEMBL27564950 0.75 CHRM5 (0.51) CHRM5ALDH1A1HSD17B10SMN1; SMN2KDM4E
SCHEMBL11518681 0.75 NPC1 (0.58) CHRM5ALDH1A1HSD17B10MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024217519-A1 PYRROLE SULFONYL DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 天地恒一制药股份有限公司 2024-10-24 WO disclosed
EP-1563011-A1 MONO AZO DYES Clariant Finance (BVI) Limited (VG) 2005-08-17 EP disclosed
WO-2004044057-A1 MONO AZO DYES CLARIANT INTERNATIONAL LTD (CH) 2004-05-27 WO disclosed
US-4705861-A AZO DYE CHEMICAL INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 1987-11-10 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed