Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.40 |
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.40 |
| ▸ | CPT1A | P50416 | 3/20 | 0.39 |
| ▸ | CPT2 | P23786 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.36 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2713636 | 1.00 | TRPV1 (0.40) | TRPV1NAA50CPT1ACPT2POLB | |
| SCHEMBL166997 | 0.91 | TRPV1 (0.43) | TRPV1NAA50CPT1ACPT2POLB | |
| SCHEMBL166998 | 0.91 | TRPV1 (0.43) | TRPV1NAA50CPT1ACPT2POLB | |
| SCHEMBL7872430 | 0.89 | TRPV1 (0.45) | TRPV1NAA50CPT1ACPT2POLB | |
| SCHEMBL6466508 | 0.89 | TRPV1 (0.40) | TRPV1NAA50CPT1ACPT2POLB | |
| SCHEMBL475428 | 0.89 | TRPV1 (0.45) | TRPV1NAA50CPT1ACPT2POLB | |
| SCHEMBL6468509 | 0.89 | TRPV1 (0.40) | TRPV1NAA50CPT1ACPT2POLB | |
| SCHEMBL6464489 | 0.89 | POLB (0.39) | TRPV1NAA50CPT1ACPT2POLB | |
| SCHEMBL475798 | 0.87 | CPT1A (0.40) | TRPV1NAA50CPT1ACPT2POLB | |
| SCHEMBL2727219 | 0.87 | CPT1A (0.49) | TRPV1NAA50CPT1ACPT2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |