Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 12/20 | 0.70 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044535 | 0.91 | NPY1R (0.75) | NPY1RCRHR1KDM4EALDH1A1MAPT | |
| SCHEMBL1593530 | 0.88 | NPY1R (0.67) | NPY1RCRHR1KDM4EALDH1A1MAPT | |
| SCHEMBL7041260 | 0.84 | NPY1R (0.78) | NPY1RCRHR1KDM4EALDH1A1MAPT | |
| SCHEMBL7044245 | 0.83 | NPY1R (1.00) | NPY1RCRHR1KDM4EALDH1A1MAPT | |
| SCHEMBL1593336 | 0.81 | NPY1R (0.79) | NPY1RCRHR1KDM4EALDH1A1MAPT | |
| SCHEMBL1594426 | 0.80 | NPY1R (0.82) | NPY1RCRHR1KDM4EALDH1A1MAPT | |
| SCHEMBL1593289 | 0.80 | NPY1R (0.78) | NPY1RCRHR1KDM4EALDH1A1MAPT | |
| SCHEMBL7039384 | 0.80 | NPY1R (0.78) | NPY1RCRHR1KDM4EALDH1A1MAPT | |
| SCHEMBL5729134 | 0.80 | NPY1R (0.85) | NPY1RCRHR1KDM4EALDH1A1MAPT | |
| SCHEMBL7039992 | 0.80 | NPY1R (0.79) | NPY1RCRHR1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585956-A2 | ASSESSMENT OF NEURONS IN THE ARCUATE NUCLEUS TO SCREEN FOR AGENTS THAT MODIFY FEEDING BEHAVIOR | Oregon Health and Science University (US) | 2005-10-19 | — | — | EP | disclosed |
| WO-2003027637-A2 | ASSESSMENT OF NEURONS IN THE ARCUATE NUCLEUS TO SCREEN FOR AGENTS THAT MODIFY FEEDING BEHAVIOR | OREGON HEALTH AND SCIENCE UNIVERSITY (US) | 2003-04-03 | — | — | WO | disclosed |