Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13452774 | 0.78 | KMT2A (0.39) | CYP1A2CHRM3 | |
| SCHEMBL4373179 | 0.78 | HTT (0.38) | CYP1A2CHRM3 | |
| SCHEMBL20093387 | 0.78 | KMT2A (0.39) | CYP1A2CHRM3 | |
| SCHEMBL12572936 | 0.78 | KMT2A (0.39) | CYP1A2CHRM3 | |
| SCHEMBL25801669 | 0.77 | CHRM3 (0.33) | CHRM3 | |
| SCHEMBL24576921 | 0.76 | MEN1 (0.33) | CYP1A2CHRM3 | |
| SCHEMBL16376633 | 0.76 | CYP1A2 (0.33) | CYP1A2CHRM3 | |
| SCHEMBL23746672 | 0.76 | POLB (0.39) | CYP1A2CHRM3 | |
| SCHEMBL21398646 | 0.76 | KMT2A (0.41) | CYP1A2CHRM3 | |
| SCHEMBL16285866 | 0.76 | POLB (0.39) | CYP1A2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119567-B1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-05-04 | — | — | EP | claimed |