Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713292 | 0.82 | GAA (0.49) | GAAMAPTNPSR1TSHRPTPRC | |
| SCHEMBL9005060 | 0.82 | GAA (0.49) | GAAMAPTNPSR1TSHRPTPRC | |
| SCHEMBL6328287 | 0.81 | GAA (0.43) | CYP3A4SMN1; SMN2GAAMAPTNPSR1 | |
| SCHEMBL28371251 | 0.81 | GAA (0.43) | CYP3A4SMN1; SMN2GAAMAPTNPSR1 | |
| SCHEMBL3057004 | 0.81 | GAA (0.48) | CYP3A4SMN1; SMN2GAAMAPTNPSR1 | |
| SCHEMBL18499649 | 0.81 | MAPT (0.50) | SMN1; SMN2GAAMAPTNPSR1PTPRC | |
| SCHEMBL18430410 | 0.77 | MAPT (0.50) | SMN1; SMN2GAAMAPTNPSR1PTPRC | |
| SCHEMBL3884152 | 0.77 | MAPT (0.50) | GAAMAPTNPSR1PTPRCKMT2A | |
| SCHEMBL20261868 | 0.77 | MAPT (0.60) | SMN1; SMN2GAAMAPTNPSR1PTPRC | |
| SCHEMBL8630112 | 0.76 | GAA (0.51) | SMN1; SMN2GAAMAPTNPSR1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | HCRTR2, MCHR1, MCHR2 | CYP3A4 284/4885SMN1; SMN2 1477/4885GAA 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.