Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 7/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.59 |
| ▸ | CYP2E1 | P05181 | 5/20 | 0.59 |
| ▸ | CYP2B6 | P20813 | 5/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | AOC1 | P19801 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922779 | 0.76 | GRM5 (0.46) | CYP2A6CYP2C19CYP2E1CYP2B6CYP2D6 | |
| SCHEMBL17050214 | 0.76 | GRM5 (0.48) | CYP2A6CYP2C19CYP2E1CYP2B6CYP2D6 | |
| SCHEMBL13907283 | 0.76 | GRM5 (0.70) | GRM5 | |
| SCHEMBL3603698 | 0.74 | CYP2A6 (1.00) | CYP2A6CYP2C19CYP2E1CYP2B6CYP2D6 | |
| SCHEMBL9257177 | 0.73 | GRM5 (0.43) | GRM5 | |
| SCHEMBL23781631 | 0.73 | CYP2A6 (0.50) | CYP2A6CYP2C19CYP2E1CYP2B6CYP2D6 | |
| SCHEMBL20409161 | 0.72 | — | — | |
| SCHEMBL4072436 | 0.71 | CYP2C19 (0.60) | CYP2A6CYP2C19CYP2E1CYP2B6CYP2D6 | |
| SCHEMBL6449000 | 0.71 | CYP2C19 (0.75) | CYP2A6CYP2C19CYP2E1CYP2B6CYP2D6 | |
| SCHEMBL14031029 | 0.70 | CYP2C19 (0.47) | CYP2A6CYP2C19CYP2E1CYP2B6CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210276987-A1 | PHARMACEUTICAL AGENTS FOR USE IN SMOKING AND TOBACCO CESSATION | WASHINGTON STATE UNIVERSITY (US) | 2021-09-09 | — | — | US | disclosed |
| EP-1015643-B1 | METHOD AND REAGENTS FOR ANALYZING THE NUCLEOTIDE SEQUENCE OF NUCLEIC ACIDS | AGILENT TECHNOLOGIES INC (US) | 2005-09-21 | — | — | EP | disclosed |
| US-20040248104-A1 | Methods and reagents for profiling quantities of nucleic acids | AGILENT TECHNOLOGIES, INC. | 2004-12-09 | — | — | US | disclosed |
| US-6218118-B1 | MIXTURE OF NATURAL AND MASS-MODIFIED GENERIC OLIGONUCLEOTIDE PRECURSORS; USING MIXTURE AND ENZYMATIC PROCESSES TO ALTER THE LENGTH, AND THUS THE MASS, OF PRECURSORS THAT ARE COMPLEMENTARY TO TARGET NUCLEIC ACID | AGILENT TECHNOLOGIES, INC. | 2001-04-17 | — | — | US | disclosed |
| EP-1015643-A2 | METHOD AND REAGENTS FOR ANALYZING THE NUCLEOTIDE SEQUENCE OF NUCLEIC ACIDS | Hewlett-Packard Company (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-2000003038-A2 | METHOD AND REAGENTS FOR ANALYZING THE NUCLEOTIDE SEQUENCE OF NUCLEIC ACIDS | HEWLETT-PACKARD COMPANY (US) | 2000-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210276987-A1 | PHARMACEUTICAL AGENTS FOR USE IN SMOKING AND TOBACCO CESSATION | CYP2A6, CYP2B6, CYP2D6 | CYP2A6 1/4885CYP2C19 51/4885CYP2E1 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.