Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4974148 | 0.90 | TRPV1 (0.82) | TRPV1 | |
| SCHEMBL4984585 | 0.87 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4977606 | 0.86 | TRPV1 (0.98) | TRPV1 | |
| SCHEMBL4977028 | 0.86 | TRPV1 (0.98) | TRPV1 | |
| SCHEMBL4971853 | 0.86 | TRPV1 (0.98) | TRPV1 | |
| SCHEMBL4976504 | 0.84 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL6469086 | 0.83 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL4977747 | 0.83 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4973292 | 0.83 | TRPV1 (0.82) | TRPV1 | |
| SCHEMBL4971882 | 0.82 | TRPV1 (0.81) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581225-A1 | COMBINATION THERAPY FOR THE TREATMENT OF PAIN | NEUROGEN CORPORATION (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004054582-A1 | COMBINATION THERAPY FOR THE TREATMENT OF PAIN | NEUROGEN CORPORATION (US) | 2004-07-01 | — | — | WO | disclosed |