SCHEMBL6469685

SCHEMBL6469685

CCCCCCCCCCP(=O)(C(=O)c1c(C)cc(C)cc1C)C(=O)c1c(C)cc(C)cc1C

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 3/20 0.40
LPAR2 Q9HBW0 1/20 0.40
ITGB1 P05556 1/20 0.40
ITGA4 P13612 1/20 0.40
HPGD P15428 2/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CETP P11597 5/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
POLB P06746 1/20 0.36
KDM4E B2RXH2 1/20 0.36
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8532958 1.00 LPAR3 (0.40) LPAR3LPAR2ITGB1ITGA4HPGD
SCHEMBL6470163 1.00 LPAR3 (0.40) LPAR3LPAR2ITGB1ITGA4HPGD
SCHEMBL28251245 1.00 LPAR3 (0.40) LPAR3LPAR2ITGB1ITGA4HPGD
SCHEMBL6467886 1.00 LPAR3 (0.40) LPAR3LPAR2ITGB1ITGA4HPGD
SCHEMBL2064034 0.98 ITGB1 (0.41) LPAR3LPAR2ITGB1ITGA4HPGD
SCHEMBL2497195 0.93 HPGD (0.41) ITGB1ITGA4HPGDMEN1LMNA
SCHEMBL5160037 0.93 KMT2A (0.39) ITGB1ITGA4HPGDMEN1LMNA
SCHEMBL1035616 0.88 KMT2A (0.40) ITGB1ITGA4HPGDMEN1LMNA
SCHEMBL5996226 0.87 LPAR3 (0.40) LPAR3LPAR2ITGB1ITGA4HPGD
SCHEMBL5996352 0.87 LPAR3 (0.40) LPAR3LPAR2ITGB1ITGA4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050096406-A1 Reactive diluents and alkyd resin coating compositions PRETOT ROGER (CH) 2005-05-05 US disclosed
US-5534559-A UNSATURATED POLYESTERS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed