SCHEMBL647078

SCHEMBL647078

PCCCCCCCCCCCCCCCCCC(c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 6/20 0.56
HTR2A P28223 6/20 0.56
SIGMAR1 Q99720 4/20 0.52
CYP19A1 P11511 3/20 0.46
TBXAS1 P24557 1/20 0.44
TAAR1 Q96RJ0 1/20 0.41
GRIN1 Q05586 2/20 0.41
GRIN2A Q12879 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1415756 1.00 HRH1 (0.56) HRH1HTR2ASIGMAR1CYP19A1TBXAS1
SCHEMBL23581510 1.00 HRH1 (0.56) HRH1HTR2ASIGMAR1CYP19A1TBXAS1
SCHEMBL17529779 1.00 HRH1 (0.56) HRH1HTR2ASIGMAR1CYP19A1TBXAS1
SCHEMBL8860226 1.00 HRH1 (0.56) HRH1HTR2ASIGMAR1CYP19A1TBXAS1
SCHEMBL5070184 0.98 HRH1 (0.58) HRH1HTR2ASIGMAR1CYP19A1TBXAS1
SCHEMBL647982 0.91 HRH1 (0.60) HRH1HTR2ASIGMAR1CYP19A1TAAR1
SCHEMBL9073997 0.85 HRH1 (0.71) HRH1HTR2ASIGMAR1CYP19A1TAAR1
SCHEMBL27015211 0.84 HRH1 (0.39) HRH1HTR2ASIGMAR1CYP19A1TAAR1
SCHEMBL258151 0.80 HRH1 (0.56) HRH1HTR2ASIGMAR1TAAR1
SCHEMBL15656561 0.78 CYP19A1 (0.46) HRH1HTR2ASIGMAR1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6476178-B1 Polycarbonate resin composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-11-05 US claimed
US-12570837-B2 Polycarbonate resin composition and molded article IDEMITSU KOSAN CO., LTD. (JP) 2026-03-10 US disclosed
EP-4692233-A1 POLYCARBONATE RESIN COMPOSITION Mitsubishi Engineering-Plastics Corporation (JP) 2026-02-11 EP disclosed
EP-3604443-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED BODY IDEMITSU KOSAN CO (JP) 2025-10-15 EP disclosed
US-12398266-B2 Polycarbonate resin composition IDEMITSU KOSAN CO., LTD. (JP) 2025-08-26 US disclosed
US-20250205637-A1 GAS SEPARATION MEMBRANE IDEMITSU KOSAN CO., LTD. (JP) 2025-06-26 US disclosed
EP-4556507-A1 POLYCARBONATE-POLYORGANOSILOXANE COPOLYMER, POLYCARBONATE RESIN COMPOSITION AND MOLDED BODY Idemitsu Kosan Co.,Ltd. (JP) 2025-05-21 EP disclosed
US-20250145819-A1 POLYCARBONATE-BASED RESIN COMPOSITION IDEMITSU KOSAN CO.,LTD. (JP) 2025-05-08 US disclosed
US-20250066586-A1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2025-02-27 US disclosed
WO-2025041769-A1 POLYCARBONATE RESIN COMPOSITION 三菱エンジニアリングプラスチックス株式会社 2025-02-27 WO disclosed
US-6548624-B2 Polycarbonate resin composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-04-15 US disclosed
US-20020193476-A1 Polycarbonate resin composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-12-19 US disclosed
US-6476178-B1 Polycarbonate resin composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-11-05 US disclosed
US-6232397-B1 Molding compounds consisting of a polycarbonate mixture and a siloxane reticular rubber BASF AKTIENGESELLSCHAFT (DE) 2001-05-15 US disclosed
EP-0600447-B1 Aromatic polycarbonate and production method thereof MITSUI CHEMICALS INC (JP) 1998-10-07 EP disclosed
US-5426170-A Interfacial polymerization of aromatic dihydroxy compound, carbonate precursor, alkali metal or alkaline metal base, water and solvent, endcapping MITSUI TOATSU CHEMICALS, INC. (JP) 1995-06-20 US disclosed
EP-0600447-A2 Aromatic polycarbonate and production method thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-06-08 EP disclosed
EP-0143906-B1 PROCESS FOR PREPARING STABILIZED POLYCARBONATE MOULDED ARTICLES BY VENTED INJECTION MOULDING OR VENTED EXTRUSION MOULDING BAYER AG (DE) 1987-06-16 EP disclosed
US-4627949-A PHOSPHINE STABILIZER BAYER AKTIENGESELLSCHAFT (DE) 1986-12-09 US disclosed
EP-0143906-A1 Process for preparing stabilized polycarbonate moulded articles by vented injection moulding or vented extrusion moulding BAYER AG (DE) 1985-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570837-B2 Polycarbonate resin composition and molded article ERCC1, POT1, BMI1 HRH1 3474/4885HTR2A 4303/4885SIGMAR1 3824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.