Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474571 | 0.89 | MAPK14 (0.51) | MAPK14P2RX7 | |
| SCHEMBL6473011 | 0.85 | MAPK14 (0.45) | MAPK14P2RX7 | |
| Hydrochloric Acid SCHEMBL6472925 | 0.83 | MAPK14 (0.48) | MAPK14P2RX7CARM1 | |
| SCHEMBL6471639 | 0.81 | MAPK14 (0.43) | MAPK14 | |
| Trifluoroacetic Acid SCHEMBL6503504 | 0.79 | MAPK14 (0.65) | MAPK14 | |
| SCHEMBL6471522 | 0.78 | MAPK14 (0.42) | MAPK14P2RX7 | |
| SCHEMBL6471941 | 0.78 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL6471656 | 0.78 | MAPK14 (0.40) | MAPK14 | |
| SCHEMBL6471439 | 0.78 | MAPK14 (0.40) | MAPK14 | |
| SCHEMBL6471710 | 0.78 | MAPK14 (0.41) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | claimed |
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |