Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267243 | 0.85 | TRPV1 (0.76) | TRPV1CA12CA1CA2CA9 | |
| SCHEMBL6468923 | 0.84 | TRPV1 (0.69) | TRPV1CA12CA1CA2CA9 | |
| SCHEMBL4273840 | 0.83 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4273828 | 0.83 | TRPV1 (0.78) | TRPV1 | |
| SCHEMBL4260347 | 0.82 | TRPV1 (0.79) | TRPV1 | |
| SCHEMBL4268876 | 0.81 | TRPV1 (0.78) | TRPV1 | |
| SCHEMBL4274918 | 0.78 | TRPV1 (0.89) | TRPV1 | |
| SCHEMBL4274898 | 0.78 | TRPV1 (0.70) | TRPV1 | |
| SCHEMBL4272762 | 0.78 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL4273890 | 0.78 | TRPV1 (0.88) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581225-A1 | COMBINATION THERAPY FOR THE TREATMENT OF PAIN | NEUROGEN CORPORATION (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004054582-A1 | COMBINATION THERAPY FOR THE TREATMENT OF PAIN | NEUROGEN CORPORATION (US) | 2004-07-01 | — | — | WO | disclosed |