Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2712146 | 1.00 | EPHX1 (0.50) | EPHX1ALDH1A1SPHK1SPHK2ALOX5 | |
| SCHEMBL28228462 | 1.00 | EPHX1 (0.50) | EPHX1ALDH1A1SPHK1SPHK2ALOX5 | |
| SCHEMBL3691 | 1.00 | EPHX1 (0.50) | EPHX1ALDH1A1SPHK1SPHK2ALOX5 | |
| SCHEMBL5797801 | 0.95 | EPHX1 (0.48) | EPHX1ALDH1A1SPHK1SPHK2CYP1A2 | |
| SCHEMBL11592604 | 0.92 | EPHX1 (0.43) | EPHX1ALDH1A1SPHK1SPHK2ALOX5 | |
| SCHEMBL9057842 | 0.92 | EPHX1 (0.43) | EPHX1ALDH1A1SPHK1SPHK2ALOX5 | |
| SCHEMBL29459695 | 0.91 | EPHX1 (0.42) | EPHX1ALDH1A1SPHK1SPHK2ALOX5 | |
| SCHEMBL3286073 | 0.91 | EPHX1 (0.42) | EPHX1ALDH1A1SPHK1SPHK2ALOX5 | |
| SCHEMBL28227693 | 0.89 | EPHX1 (0.59) | EPHX1ALDH1A1SPHK1SPHK2ALOX5 | |
| SCHEMBL28227694 | 0.89 | EPHX1 (0.59) | EPHX1ALDH1A1SPHK1SPHK2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041893-A2 | DETECTION OF ACUTE MYOCARDIAL INFARCTION BIOMARKERS | QUESTSTAR MEDICAL, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| EP-0451211-A4 | CLONING AND PRODUCTION OF POLYPEPTIDE ANALOGS OF HUMAN FIBRONECTIN AND METHOD OF USING SUCH POLYPEPTIDE ANALOGS | — | 1992-09-09 | — | — | EP | disclosed |
| EP-0451211-A1 | CLONING AND PRODUCTION OF POLYPEPTIDE ANALOGS OF HUMAN FIBRONECTIN AND METHOD OF USING SUCH POLYPEPTIDE ANALOGS | BIO-TECHNOLOGY GENERAL CORPORATION (US) | 1991-10-16 | — | — | EP | disclosed |
| WO-1990007577-A1 | CLONING AND PRODUCTION OF POLYPEPTIDE ANALOGS OF HUMAN FIBRONECTIN AND METHOD OF USING SUCH POLYPEPTIDE ANALOGS | BIO-TECHNOLOGY GENERAL CORP. (US) | 1990-07-12 | — | — | WO | disclosed |