Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6471715 | 0.86 | MAPK14 (0.46) | MAPK14PTGER1 | |
| Hydrochloric Acid SCHEMBL6471079 | 0.84 | MAPK14 (0.45) | MAPK14PTGER1 | |
| SCHEMBL6471896 | 0.84 | MAPK14 (0.49) | MAPK14PTGER1 | |
| Hydrochloric Acid SCHEMBL6471206 | 0.83 | MAPK14 (0.42) | MAPK14PTGER1 | |
| Hydrochloric Acid SCHEMBL6471035 | 0.83 | MAPK14 (0.49) | MAPK14PTGER1 | |
| SCHEMBL6471426 | 0.82 | MAPK14 (0.48) | MAPK14PTGER1 | |
| SCHEMBL6470992 | 0.80 | MAPK14 (0.54) | MAPK14PTGER1 | |
| SCHEMBL6471501 | 0.76 | PTGER1 (0.49) | MAPK14PTGER1 | |
| SCHEMBL6471882 | 0.76 | MAPK14 (0.44) | MAPK14MEN1KMT2APTGER1 | |
| SCHEMBL6471935 | 0.76 | MAPK14 (0.43) | MAPK14PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |