SCHEMBL6471077

SCHEMBL6471077

CS(=O)(=O)C(CCCCN)(COC1CCCCO1)S(C)(=O)=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6389445 0.79 MEN1 (0.33) MEN1KMT2A
SCHEMBL6391146 0.75 MEN1 (0.34) MEN1KMT2A
SCHEMBL8971720 0.73 MEN1 (0.48) MEN1KMT2A
SCHEMBL25865981 0.72 MEN1 (0.50) MEN1KMT2A
SCHEMBL6952808 0.72 MEN1 (0.50) MEN1KMT2A
SCHEMBL14389110 0.72 MEN1 (0.50) MEN1KMT2A
SCHEMBL26157632 0.72 MEN1 (0.50) MEN1KMT2A
SCHEMBL6947738 0.72 MEN1 (0.50) MEN1KMT2A
SCHEMBL20977729 0.72 MEN1 (0.50) MEN1KMT2A
SCHEMBL6953888 0.72 MEN1 (0.50) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1497247-A2 MIMICS OF ACYL COENZYME-A, COMPOSITIONS THEREOF, AND METHODS OF CHOLESTEROL MANAGEMENT AND RELATED USES Esperion Therapeutics Inc. (US) 2005-01-19 EP disclosed
WO-2003087108-A2 MIMICS OF ACYL COENZYME-A, COMPOSITIONS THEREOF, AND METHODS OF CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS, INC. (US) 2003-10-23 WO disclosed