Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4975222 | 0.89 | TRPV1 (0.84) | TRPV1 | |
| SCHEMBL14283302 | 0.89 | TRPV1 (0.84) | TRPV1 | |
| SCHEMBL14283303 | 0.86 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL4973307 | 0.86 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL4972387 | 0.84 | TRPV1 (0.83) | TRPV1 | |
| SCHEMBL4971809 | 0.84 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL14283305 | 0.84 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL4973809 | 0.83 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL14283309 | 0.83 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL4971924 | 0.82 | TRPV1 (0.66) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581225-A1 | COMBINATION THERAPY FOR THE TREATMENT OF PAIN | NEUROGEN CORPORATION (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004054582-A1 | COMBINATION THERAPY FOR THE TREATMENT OF PAIN | NEUROGEN CORPORATION (US) | 2004-07-01 | — | — | WO | disclosed |