Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | STRADA | Q7RTN6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472855 | 0.93 | PTGER1 (0.44) | MAOBMAPK14PTGER1KDM5AKDM4C | |
| SCHEMBL6471916 | 0.93 | PTGER1 (0.45) | MAOBMAPK14PTGER1 | |
| SCHEMBL6474423 | 0.93 | MAPK14 (0.44) | MAOBMAPK14PTGER1PPARAROCK2 | |
| SCHEMBL6474395 | 0.91 | MAPK14 (0.51) | MAOBMAPK14PTGER1ROCK2MAPK12 | |
| SCHEMBL6471261 | 0.91 | PTGER1 (0.42) | MAOBMAPK14PTGER1PPARAROCK2 | |
| SCHEMBL6532902 | 0.91 | PTGER1 (0.47) | MAOBMAPK14PTGER1 | |
| SCHEMBL6472384 | 0.90 | PTGER1 (0.44) | MAOBMAPK14PTGER1KDM5AKDM4C | |
| SCHEMBL6471427 | 0.90 | MAPK14 (0.46) | MAPK14PTGER1PPARA | |
| SCHEMBL6533709 | 0.90 | MAPK14 (0.52) | MAOBMAPK14PTGER1ROCK2MAPK12 | |
| SCHEMBL6472799 | 0.89 | MAOB (0.44) | MAOBMAPK14PTGER1ROCK2MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052366-A9 | 2-AMINOCARBONYL-QUINOLINE COMPOUNDS AS PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AG (DE) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |