Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.62 |
| ▸ | NPY1R | P25929 | 6/20 | 0.62 |
| ▸ | NPY2R | P49146 | 4/20 | 0.62 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.52 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471509 | 1.00 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL6473554 | 0.95 | NPY4R (0.68) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL6473543 | 0.95 | NPY4R (0.68) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL6472563 | 0.95 | NPY4R (0.68) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL6472571 | 0.95 | NPY4R (0.68) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL6471476 | 0.92 | NPY4R (0.64) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL6472542 | 0.92 | NPY4R (0.64) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL6471159 | 0.92 | NPY4R (0.64) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL6472534 | 0.92 | NPY4R (0.64) | NPY4RNPY1RNPY2RNPY5ROPRK1 | |
| SCHEMBL6471412 | 0.92 | NPY4R (0.64) | NPY4RNPY1RNPY2RNPY5ROPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040802-A2 | CYLIN BINDING PEPTIDES, AND THEIR USE IN DRUG SCREENING ASSAYS | CYCLACEL LIMITED (GB) | 2005-05-06 | — | — | WO | disclosed |
| EP-1250353-A2 | P21 DERIVED PEPTIDES CAPABLE OF INHIBITING CDK/CYCLIN COMPLEXES | Cyclacel Limited (GB) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001040142-A2 | P21 DERIVED PEPTIDES CAPABLE OF INHIBITING CDK/CYCLIN COMPLEXES | CYCLACEL LIMITED (GB) | 2001-06-07 | — | — | WO | disclosed |