Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CTBP2 | P56545 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746636 | 0.86 | AKR1B1 (0.46) | CYP1A2CYP2D6CYP2C9CYP2C19AKR1B1 | |
| SCHEMBL6472113 | 0.83 | CYP1A2 (0.46) | CYP1A2CYP2D6CYP2C9CYP2C19MAPK8 | |
| SCHEMBL6474059 | 0.81 | TAAR1 (0.46) | CYP1A2CYP2D6CYP2C9CYP2C19MAPK8 | |
| SCHEMBL11467086 | 0.80 | AKR1B1 (0.42) | AKR1B1TDP1CTBP2CES2CES1 | |
| SCHEMBL30561548 | 0.79 | AKR1B1 (0.61) | CYP1A2CYP2D6CYP2C9CYP2C19MAPK8 | |
| SCHEMBL314806 | 0.79 | AKR1B1 (0.61) | CYP1A2CYP2D6CYP2C9CYP2C19MAPK8 | |
| SCHEMBL1137307 | 0.78 | AKR1B1 (0.67) | CYP2D6AKR1B1TAAR1IDO1SIGMAR1 | |
| SCHEMBL7336703 | 0.78 | AKR1B1 (0.41) | AKR1B1TDP1CTBP2ALDH1A1MAPT | |
| SCHEMBL3246425 | 0.77 | CYP1A2 (0.58) | CYP1A2CYP2D6CYP2C9CYP2C19MAPK8 | |
| SCHEMBL1627494 | 0.77 | CTBP2 (0.59) | AKR1B1CTBP2KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005109041-A1 | COMPOSITIONS FOR USE IN THE MANUFACTURE OF LENSES | MEDICAL POLYMERS LIMITED (GB) | 2005-11-17 | — | — | WO | disclosed |
| US-6040408-A | Radiopaque polymers and methods for preparation thereof | BIOMAT B.V. (NL) | 2000-03-21 | — | — | US | disclosed |
| EP-0777503-B1 | RADIOPAQUE POLYMERS AND METHODS FOR PREPARATION THEREOF | BIOMAT BV (NL) | 1999-11-17 | — | — | EP | disclosed |
| EP-0777503-A1 | RADIOPAQUE POLYMERS AND METHODS FOR PREPARATION THEREOF | Biomat B.V. (NL) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005872-A1 | RADIOPAQUE POLYMERS AND METHODS FOR PREPARATION THEREOF | BIOMAT B.V. (NL) | 1996-02-29 | — | — | WO | disclosed |