Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 18/20 | 0.58 |
| ▸ | NPY1R | P25929 | 11/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.58 |
| ▸ | NPY2R | P49146 | 7/20 | 0.58 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967673 | 0.89 | NPY4R (0.61) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29385243 | 0.88 | NPY4R (0.62) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30490413 | 0.88 | NPY4R (0.62) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29666908 | 0.88 | NPY4R (0.62) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30355277 | 0.88 | NPY4R (0.62) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30490411 | 0.88 | NPY4R (0.62) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29872588 | 0.88 | NPY4R (0.62) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL24049263 | 0.88 | NPY4R (0.56) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29967116 | 0.88 | NPY4R (0.56) | NPY4RNPY1RNPY5RNPY2RNMT2 | |
| SCHEMBL25867984 | 0.88 | NPY4R (0.56) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040802-A2 | CYLIN BINDING PEPTIDES, AND THEIR USE IN DRUG SCREENING ASSAYS | CYCLACEL LIMITED (GB) | 2005-05-06 | — | — | WO | disclosed |
| EP-1250353-A2 | P21 DERIVED PEPTIDES CAPABLE OF INHIBITING CDK/CYCLIN COMPLEXES | Cyclacel Limited (GB) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001040142-A2 | P21 DERIVED PEPTIDES CAPABLE OF INHIBITING CDK/CYCLIN COMPLEXES | CYCLACEL LIMITED (GB) | 2001-06-07 | — | — | WO | disclosed |