Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | STRADA | Q7RTN6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475153 | 0.89 | MAPK14 (0.55) | MAPK14PTGER1MAOBROCK2MAPK12 | |
| SCHEMBL6472799 | 0.86 | MAOB (0.44) | MAPK14PTGER1MAOBROCK2MAPK12 | |
| SCHEMBL6471353 | 0.86 | MAPK14 (0.54) | MAPK14PTGER1MAOBROCK2MAPK12 | |
| SCHEMBL6472561 | 0.84 | MAPK14 (0.53) | MAPK14MAOBROCK2MAPK12MAPK11 | |
| SCHEMBL6471477 | 0.82 | MAPK14 (0.45) | MAPK14PTGER1MAOBROCK2MAPK12 | |
| SCHEMBL6471953 | 0.81 | MAPK14 (0.41) | MAPK14 | |
| SCHEMBL6474304 | 0.81 | PTGER1 (0.43) | MAPK14PTGER1MAOB | |
| SCHEMBL6473360 | 0.80 | MAPK14 (0.55) | MAPK14PTGER1 | |
| SCHEMBL6473316 | 0.80 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL6475003 | 0.80 | MAPK14 (0.52) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |