Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473223 | 0.85 | MAPK14 (0.43) | MAPK14 | |
| SCHEMBL6472612 | 0.84 | MAPK14 (0.47) | MAPK14 | |
| SCHEMBL6472442 | 0.83 | MAPK14 (0.57) | MAPK14 | |
| SCHEMBL6471587 | 0.82 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL6472833 | 0.82 | MAPK14 (0.54) | MAPK14 | |
| SCHEMBL6471870 | 0.81 | MAPK14 (0.41) | MAPK14 | |
| SCHEMBL6471706 | 0.79 | MAPK14 (0.45) | MAPK14 | |
| SCHEMBL6471928 | 0.79 | MAPK14 (0.40) | MAPK14 | |
| SCHEMBL6471656 | 0.78 | MAPK14 (0.40) | MAPK14 | |
| SCHEMBL6471439 | 0.78 | MAPK14 (0.40) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |