SCHEMBL647259

SCHEMBL647259

CC[CH]NC(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8514925 0.78
SCHEMBL1043899 0.75
SCHEMBL16716 0.75
SCHEMBL3374213 0.75
SCHEMBL10938420 0.73
SCHEMBL8683931 0.71
SCHEMBL3373148 0.71
SCHEMBL2975404 0.71
SCHEMBL3020276 0.71
SCHEMBL6973956 0.70 CA12 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 377 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230125046-A1 CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) 2023-04-20 US claimed
CN-113087671-B Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof 北京赛特明强医药科技有限公司 2022-10-21 CN claimed
CN-114502362-A Contact lenses with surfaces of varying softness 爱尔康公司 2022-05-13 CN claimed
CN-113087671-A Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof 北京赛特明强医药科技有限公司 2021-07-09 CN claimed
WO-2021129561-A1 CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 北京赛特明强医药科技有限公司 2021-07-01 WO claimed
CN-111566517-A Contact lenses having lubricious coating thereon 爱尔康公司 2020-08-21 CN claimed
EP-2984111-A1 PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM ExxonMobil Chemical Patents Inc. (US) 2016-02-17 EP claimed
WO-2014169017-A1 PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-10-16 WO claimed
US-8202876-B2 Compounds and compositions as protein kinase inhibitors IRM LLC (BM) 2012-06-19 US claimed
US-8012956-B2 Tropane compounds EXELIXIS, INC. (US) 2011-09-06 US claimed
EP-1226129-A1 METHODS AND COMPOSITIONS UTILIZING QUINAZOLINONES Cytokinetics, Inc. (US) 2002-07-31 EP claimed
WO-2001098278-A1 METHODS AND COMPOSITIONS UTILIZING QUINAZOLINONES CYTOKINETICS, INC. (US) 2001-12-27 WO claimed
WO-2001030768-A1 METHODS AND COMPOSITIONS UTILIZING QUINAZOLINONES CYTOKINETICS, INC. (US) 2001-05-03 WO claimed
US-5725882-A POLYSILOXANE GRAFT OR BLOCK POLYMERS FOR COSMETICS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-10 US claimed
EP-0714275-A1 POLYMERS IN COSMETICS AND PERSONAL CARE PRODUCTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-05 EP claimed
EP-0412770-B1 Polysiloxane-grafted copolymer topical binder composition with novel hydrophilic monomers and method of coating therewith MINNESOTA MINING & MFG (US) 1995-10-04 EP claimed
US-RE34958-E Methacrylate polymer for adhesives, seals and binders MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-30 US claimed
EP-0639969-A1 POLYMERS IN COSMETICS AND PERSONAL CARE PRODUCTS. MINNESOTA MINING & MFG (US) 1995-03-01 EP claimed
WO-1995003776-A1 POLYMERS IN COSMETICS AND PERSONAL CARE PRODUCTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-09 WO claimed
WO-1993023009-A1 POLYMERS IN COSMETICS AND PERSONAL CARE PRODUCTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-25 WO claimed