Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 9/20 | 0.50 |
| ▸ | MPC2 | O95563 | 2/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5762703 | 0.94 | FFAR1 (0.61) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6477734 | 0.92 | FFAR1 (0.51) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5382953 | 0.91 | FFAR1 (0.54) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5382574 | 0.91 | FFAR1 (0.53) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5760239 | 0.90 | HSD17B2 (0.56) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5762215 | 0.89 | FFAR1 (0.54) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5396096 | 0.89 | FFAR1 (0.51) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5383709 | 0.89 | FFAR1 (0.51) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5760195 | 0.89 | FFAR1 (0.52) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5389745 | 0.88 | FFAR1 (0.55) | FFAR1PPARGMPC2CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908939-B2 | Biaromatic ligand activators of PPARγ receptors | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2005-06-21 | — | — | US | claimed |