Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 11/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473305 | 0.91 | HSD17B2 (0.53) | AOC3HSD17B2HSD17B1MEN1KMT2A | |
| SCHEMBL6184210 | 0.83 | HSD17B2 (0.56) | AOC3HSD17B2HSD17B1MEN1KMT2A | |
| SCHEMBL6184250 | 0.81 | HSD17B2 (0.57) | AOC3HSD17B2HSD17B1MEN1KMT2A | |
| SCHEMBL6473087 | 0.81 | HSD17B2 (0.54) | AOC3HSD17B2HSD17B1MEN1KMT2A | |
| SCHEMBL6182236 | 0.78 | HSD17B2 (0.62) | AOC3HSD17B2HSD17B1MEN1KMT2A | |
| SCHEMBL2851697 | 0.78 | HSD17B2 (0.58) | AOC3HSD17B2HSD17B1MEN1KMT2A | |
| SCHEMBL2847856 | 0.78 | HSD17B2 (0.58) | AOC3HSD17B2HSD17B1MEN1KMT2A | |
| SCHEMBL3439044 | 0.78 | HSD17B2 (0.58) | AOC3HSD17B2HSD17B1MEN1KMT2A | |
| SCHEMBL6184066 | 0.78 | HSD17B2 (0.58) | AOC3HSD17B2HSD17B1MEN1KMT2A | |
| SCHEMBL11363429 | 0.78 | AOC3 (0.81) | AOC3HSD17B2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927228-B2 | Biphenyl compounds usefuf in treatment of human and veterinary medicines such as dermatology, cardivovascular diseases, immune diseases or diseases associated with lipid metabolisms, or in cosmetic formulation | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-08-09 | — | — | US | disclosed |
| US-20040039038-A1 | Biaromatic compound activators of PPARy-type receptors | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039038-A1 | Biaromatic compound activators of PPARy-type receptors | PPARG, PPARA, PPARD | AOC3 1747/4885HSD17B2 368/4885HSD17B1 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.