SCHEMBL6473262

SCHEMBL6473262

O=C(O)CCCN1C(=O)C=CC1=O.O=C(O)CCCN1C(=O)C=CC1=O.[KH].[KH].[KH].[KH]

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 7/20 0.81
PTGS2 P35354 7/20 0.81
MGLL Q99685 7/20 0.60
FAAH O00519 4/20 0.60
HSP90AA1 P07900 1/20 0.58
TLR9 Q9NR96 1/20 0.58
ALDH1A1 P00352 1/20 0.58
LMNA P02545 1/20 0.58
TP53 P04637 1/20 0.58
MAPT P10636 1/20 0.58
PKM P14618 1/20 0.58
HPGD P15428 1/20 0.58
XBP1 P17861 1/20 0.58
MAPK1 P28482 1/20 0.58
HTT P42858 1/20 0.58
RECQL P46063 1/20 0.58
RAB9A P51151 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
GPR35 Q9HC97 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3049679 1.00 PTGS1 (0.81) PTGS1PTGS2MGLLFAAHHSP90AA1
SCHEMBL155346 0.98 PTGS1 (0.85) PTGS1PTGS2MGLLFAAHHSP90AA1
SCHEMBL3047985 0.96 PTGS1 (0.81) PTGS1PTGS2MGLLFAAHHSP90AA1
Hydrochloric Acid SCHEMBL17924135 0.96 PTGS1 (0.81) PTGS1PTGS2MGLLFAAHHSP90AA1
SCHEMBL17764749 0.96 PTGS1 (0.81) PTGS1PTGS2MGLLFAAHHSP90AA1
SCHEMBL2722163 0.92 PTGS1 (0.96) PTGS1PTGS2MGLLFAAHHSP90AA1
SCHEMBL27802760 0.90 PTGS1 (0.73) PTGS1PTGS2MGLLFAAHHSP90AA1
Alcohol SCHEMBL29133178 0.90 PTGS1 (0.73) PTGS1PTGS2MGLLFAAHHSP90AA1
SCHEMBL24939859 0.90 PTGS1 (1.00) PTGS1PTGS2MGLLFAAHHSP90AA1
SCHEMBL3291535 0.90 PTGS1 (1.00) PTGS1PTGS2MGLLFAAHHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1525002-A1 METHOD FOR THE SYNTHESIS OF ANTHRACYCLINE-PEPTIDE CONJUGATES UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) 2005-04-27 EP disclosed
WO-2004011033-A1 METHOD FOR THE SYNTHESIS OF ANTHRACYCLINE-PEPTIDE CONJUGATES UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) 2004-02-05 WO disclosed