Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Purine SCHEMBL3021752 | 0.80 | KDM4A (0.36) | — | |
| Purine SCHEMBL3157 | 0.80 | — | — | |
| Purine SCHEMBL2120547 | 0.80 | KDM4A (0.38) | XDH | |
| Purine SCHEMBL6438162 | 0.78 | KDM4A (0.37) | — | |
| Purine SCHEMBL9603027 | 0.78 | — | — | |
| Purine SCHEMBL311318 | 0.78 | KDM4A (0.37) | — | |
| Tetrabuthylammonium SCHEMBL6473275 | 0.76 | PAK1 (0.41) | SLC22A1HRH3XDHPAK1CDK1 | |
| Purine SCHEMBL20520352 | 0.75 | KDM4A (0.39) | — | |
| Purine SCHEMBL1827535 | 0.75 | KDM4A (0.35) | — | |
| Purine SCHEMBL7787939 | 0.73 | KDM4A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1535923-A1 | Synthesis of acyclic nucleoside derivatives | Medivir Aktiebolag (SE) | 2005-06-01 | — | — | EP | disclosed |
| EP-1131323-A1 | SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES | Medivir Aktiebolag (SE) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000008025-A1 | SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES | MEDIVIR AB (SE) | 2000-02-17 | — | — | WO | disclosed |