Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | AGXT | P21549 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | GRM5 | P41594 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13450401 | 0.82 | MAOB (0.60) | MAOBIDO1AGXTGSK3BBACE1 | |
| SCHEMBL14329911 | 0.81 | MAOB (0.49) | MAOBIDO1AGXTGSK3BBACE1 | |
| SCHEMBL7024898 | 0.81 | MAOB (0.68) | MAOBIDO1AGXTGSK3BBACE1 | |
| SCHEMBL4886506 | 0.80 | MAOB (0.58) | MAOBIDO1AGXTGSK3BBACE1 | |
| SCHEMBL4339666 | 0.79 | MAOB (0.61) | MAOBIDO1AGXTGSK3BBACE1 | |
| SCHEMBL3216377 | 0.79 | MAOB (0.57) | MAOBIDO1AGXTGSK3BBACE1 | |
| SCHEMBL28366212 | 0.79 | MAOB (0.60) | MAOBIDO1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL5514364 | 0.77 | MAOB (0.62) | MAOBIDO1AGXTGSK3BBACE1 | |
| SCHEMBL4380683 | 0.77 | MAOB (0.55) | MAOBIDO1AGXTGSK3BBACE1 | |
| SCHEMBL5511238 | 0.77 | MAOB (0.58) | MAOBIDO1AGXTGSK3BBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |