Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475260 | 0.87 | CA12 (0.49) | XDHCA12CA1CA2CA7 | |
| SCHEMBL6471350 | 0.85 | CA12 (0.47) | XDHCA12CA1CA2CA7 | |
| SCHEMBL4977924 | 0.85 | CA12 (0.49) | XDHCA12CA1CA2CA7 | |
| SCHEMBL6471904 | 0.82 | CA12 (0.47) | XDHCA12CA1CA2CA7 | |
| SCHEMBL6473741 | 0.82 | CA12 (0.47) | XDHCA12CA1CA2CA7 | |
| SCHEMBL6472993 | 0.80 | CA12 (0.49) | XDHCA12CA1CA2CA7 | |
| SCHEMBL6471298 | 0.77 | ERN1 (0.49) | XDHCA12CA1CA2CA7 | |
| SCHEMBL6472603 | 0.77 | KDM4E (0.40) | XDHCA12CA1CA2CA7 | |
| SCHEMBL6471654 | 0.76 | CNR2 (0.55) | XDHCA12CA1CA2CA7 | |
| SCHEMBL6471366 | 0.75 | KDM4E (0.38) | XDHCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |