Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.48 |
| ▸ | IL1RN | P18510 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tryptophan SCHEMBL6473526 | 1.00 | KMT2A (0.54) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL27537413 | 0.97 | KMT2A (0.57) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL22635845 | 0.92 | KDM4E (0.64) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL18249969 | 0.89 | KDM4E (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL27895091 | 0.89 | KDM4E (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL29183929 | 0.89 | KDM4E (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Tyrosine SCHEMBL3131438 | 0.87 | SLC7A5 (0.53) | OPRD1LTA4H | |
| Tyrosine SCHEMBL3131428 | 0.87 | SLC7A5 (0.53) | OPRD1LTA4H | |
| Dl-Tryptophan SCHEMBL20504023 | 0.87 | KDM4E (0.71) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL27662421 | 0.87 | KDM4E (0.61) | KMT2AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110124-A1 | COMPOSITION AND METHODS FOR NUTRITIONAL MANAGEMENT OF PATIENTS WITH HEPATIC DISEASE | ABBOTT LABORATORIES (US) | 2005-11-24 | — | — | WO | disclosed |