Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472180 | 0.91 | MAPK14 (0.43) | MAPK14PTGER1 | |
| SCHEMBL6471929 | 0.85 | MAPK14 (0.37) | MAPK14PTGER1GSK3BBACE1 | |
| SCHEMBL6472799 | 0.84 | MAOB (0.44) | MAPK14CYP1A1CYP1A2CYP1B1PTGER1 | |
| SCHEMBL6474304 | 0.82 | PTGER1 (0.43) | MAPK14PTGER1 | |
| SCHEMBL6472896 | 0.82 | MAPK14 (0.41) | MAPK14 | |
| SCHEMBL6471547 | 0.81 | PTGER1 (0.49) | MAPK14PTGER1 | |
| SCHEMBL6471953 | 0.81 | MAPK14 (0.41) | MAPK14CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL6471353 | 0.79 | MAPK14 (0.54) | MAPK14PTGER1 | |
| SCHEMBL6472384 | 0.79 | PTGER1 (0.44) | MAPK14PTGER1 | |
| SCHEMBL6471462 | 0.79 | MAPK14 (0.44) | MAPK14PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | claimed |
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |