SCHEMBL647403

SCHEMBL647403

[CH]=CCC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27502787 0.74
SCHEMBL27785210 0.74
SCHEMBL11517608 0.70
SCHEMBL16527580 0.70
SCHEMBL28161197 0.70
SCHEMBL2375897 0.70
SCHEMBL865450 0.67
SCHEMBL1470231 0.67
SCHEMBL11515548 0.66
SCHEMBL3342425 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8372854-B2 Pyrrolo[2,3-D]pyrimidine compounds PFIZER INC. (US) 2013-02-12 US claimed
EP-2513114-A1 PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS Pfizer Inc. (US) 2012-10-24 EP claimed
US-20110294826-A1 PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS PFIZER INC. (US) 2011-12-01 US claimed
WO-2011075334-A1 PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS PFIZER INC. (US) 2011-06-23 WO claimed
US-5162351-A Nematocides SCHERING AKTIENGESELLSCHAFT (DE) 1992-11-10 US claimed
US-4748186-A NEMATOCIDES, ANTHELMINTICS FMC CORPORATION (US) 1988-05-31 US claimed
WO-1988000183-A1 S-TRIFLUOROBUTENYL DERIVATIVES AND PESTICIDAL USES FMC CORPORATION (US) 1988-01-14 WO claimed
CN-114075254-B Chitosan oligosaccharide derivative wire-killing agent and preparation method and application thereof 佛山市海力盈生物科技有限公司 2024-01-30 CN disclosed
US-RE49686-E1 Nitrogen-containing heterocyclic compound and use of same TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-10-10 US disclosed
WO-2023176458-A1 DISINFECTING COMPOSITION CONTAINING THIAZOLE CARBOXYLIC ACID HYDRAZIDE COMPOUND 石原産業株式会社 2023-09-21 WO disclosed
CN-114075300-B Chitosan oligosaccharide derivative nematicide and preparation method and application thereof 佛山市海力盈生物科技有限公司 2023-02-28 CN disclosed
US-20220089532-A1 BENZENE DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2022-03-24 US disclosed
US-11261154-B2 Benzene derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2022-03-01 US disclosed
EP-0228447-A4 PESTICIDAL POLYHALOALKENE DERIVATIVES 1990-12-27 EP disclosed
US-4952580-A NEMATOCIDES, ANTHELMINTICS FMC CORPORATION (US) 1990-08-28 US disclosed
US-4748186-A NEMATOCIDES, ANTHELMINTICS FMC CORPORATION (US) 1988-05-31 US disclosed
US-4748186-A NEMATOCIDES, ANTHELMINTICS FMC CORPORATION (US) 1988-05-31 US disclosed
WO-1988000183-A1 S-TRIFLUOROBUTENYL DERIVATIVES AND PESTICIDAL USES FMC CORPORATION (US) 1988-01-14 WO disclosed
EP-0228447-A1 PESTICIDAL POLYHALOALKENE DERIVATIVES FMC Corporation (US) 1987-07-15 EP disclosed
WO-1986007590-A1 PESTICIDAL POLYHALOALKENE DERIVATIVES FMC CORPORATION (US) 1986-12-31 WO disclosed