Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6533399 | 0.91 | MAPK14 (0.45) | MAPK14 | |
| SCHEMBL6472738 | 0.90 | MAPK14 (0.44) | MAPK14ALDH1A1 | |
| SCHEMBL6472007 | 0.85 | MAPK14 (0.48) | MAPK14 | |
| Hydrochloric Acid SCHEMBL6472381 | 0.83 | MAPK14 (0.49) | MAPK14 | |
| SCHEMBL6474959 | 0.83 | MAPK14 (0.49) | MAPK14 | |
| Hydrochloric Acid SCHEMBL6472357 | 0.81 | MAPK14 (0.46) | MAPK14 | |
| Hydrochloric Acid SCHEMBL6474992 | 0.81 | MAPK14 (0.46) | MAPK14 | |
| Hydrochloric Acid SCHEMBL6472999 | 0.81 | MAPK14 (0.46) | MAPK14 | |
| Hydrochloric Acid SCHEMBL6473612 | 0.81 | MAPK14 (0.43) | MAPK14SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6471433 | 0.80 | MAPK14 (0.47) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |