SCHEMBL64756

SCHEMBL64756

C=CC(=O)OC(F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.34
ALDH1A1 P00352 4/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31195752 0.84 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2777665 0.83 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL41966 0.83 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8451860 0.83 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL42441 0.81 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3902256 0.81 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2450860 0.80 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL63734 0.79 TSHR (0.31) TSHR
SCHEMBL1149531 0.79 TSHR (0.31) TSHR
SCHEMBL9715099 0.79 TSHR (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447642-A In-situ phase separation ionic gel adhesive and preparation method and application thereof 香港中文大学(深圳) 2024-01-26 CN claimed
CN-116404159-A Adhesive, and preparation method and application thereof 上海华谊三爱富新材料有限公司 2023-07-07 CN claimed
CN-111995771-B Phase-change ion gel, preparation method thereof and ion device 香港中文大学(深圳) 2023-04-28 CN claimed
CN-111995771-A Phase-change ion gel, preparation method thereof and ion device 香港中文大学(深圳) 2020-11-27 CN claimed
US-8524800-B2 Actinically curable silicone hydrogel copolymers and uses thereof NOVARTIS AG (CH) 2013-09-03 US claimed
WO-2013015670-A1 A SELF-PLASTICIZED SENSING MEMBRANE MIMOS BERHAD (MY) 2013-01-31 WO claimed
US-20080143003-A1 Actinically curable silicone hydrogel copolymers and uses thereof ALCON INC. (CH) 2008-06-19 US claimed
US-5214097-A Blends with vinyl block copolymer and diene or olefin rubber DAIKIN INDUSTRIES LTD. (JP) 1993-05-25 US claimed
US-4387203-A COPOLYMER OF AN UNSATURATED NITRILE, CONJUGATED DIENE AND UNSATURATED FLUORINE COMPOUND GASOLINE RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-06-07 US claimed
CN-114207050-B Composite particles comprising a hydrophobic dye and an amphiphilic block copolymer and their use in optical applications 史密斯实验室公司 2024-12-13 CN disclosed
US-12116468-B2 Composite particles comprising a hydrophobic dye and an amphiphilic block copolymer and use thereof in optical applications COLOURSMITH LABS INC. (CA) 2024-10-15 US disclosed
WO-2024167161-A1 COLORED PHOTOSENSITIVE RESIN COMPOSITION AND COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE MANUFACTURED USING SAME 동우 화인켐 주식회사 2024-08-15 WO disclosed
US-12037463-B2 Antimicrobial ophthalmic devices comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-16 US disclosed
US-12024597-B2 Wound dressings comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-02 US disclosed
US-5486544-A AROMATIC SULFINATE POLYMERIZATION CATALYST KURARAY CO., LTD. (JP) 1996-01-23 US disclosed
US-5214097-A Blends with vinyl block copolymer and diene or olefin rubber DAIKIN INDUSTRIES LTD. (JP) 1993-05-25 US disclosed
EP-0458195-A2 Fluororubber composition DAIKIN INDUSTRIES, LIMITED (JP) 1991-11-27 EP disclosed
US-4725521-A BLENDED COATING OF TETRAFLUOROETHYLENE-VINYLIDENE FLUORIDE COPOLYMER AND FLUORINATED ACRYLATE POLYMER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-02-16 US disclosed
US-4387203-A COPOLYMER OF AN UNSATURATED NITRILE, CONJUGATED DIENE AND UNSATURATED FLUORINE COMPOUND GASOLINE RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-06-07 US disclosed
US-4046577-A PHOTOREACTIVE COMPOSITIONS COMPRISING POLYMERS CONTAINING ALKOXYAROMATIC GLYOXY GROUPS THE RICHARDSON COMPANY (US) 1977-09-06 US disclosed